The emergence of yellow stains on the skin (xanthelasmata) at the top of the eyelid may be a marker of risk of an individual suffering from heart disease. The study, led by Professor Anne Tybjarg-Hansen at the University of Copenhagen is also concluded that the ring of white or gray around the cornea (arcus corneae) not related risk of heart disease.
Previous studies have established that both xanthelasmata and arcus corneae are cholesterol deposits. However, about half of the individuals who have one or both of the above conditions did not have the high cholesterol positive through blood tests.
These results led researchers to investigate the relationship between xanthelasmata and arcus corneae on the risk of heart attack, heart disease, stroke, arterial thickening or early death in the general population.
The researchers surveyed 12,745 people who participated in the Copenhagen City heart study. The participants were aged between 20 to 93 years and did not develop heart disease when the study began. They monitored since 1976 until May 2009.
At the beginning of the study, a total of 563 participants (4.4%) had xanthelasmata and 3159 people (24.8%) had arcus corneae. During follow-up, 1872 participants had a heart attack, 3699 people have heart disease, 1498 people suffered a stroke, cerebrovascular disease 1815 people and 8507 people died.
The results showed that the risk of heart attack, heart disease or death within a period of ten years, an increase in individuals who have xanthelasmata, both men and women in all age groups.
The increased risk was independent of other known risk factors such as gender, smoking habits, obesity, high blood pressure, and cholesterol levels.
The highest risk was found in men aged 70 to 79 years. The risk of heart problems in the male participants who had xanthelasmata by 53%. Higher than 41% for men without xanthelasmata.
Whereas in women who have experienced 35% xanthelasmata risk of heart problems.Higher than that do not have the xanthelasmata, amounting to 27%.
Conversely, esciencenews.com study released This shows that the arcus corneae is not a significant predictor for the risk of heart attack or heart disease.
The researchers concluded that the emergence xanthelasmata can assist physicians in diagnosing heart problems. They added that their findings can be very useful in society that are difficult to access the laboratory to perform measurements of fat.
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