“Pre-menopausal women who carry excess fat in the abdominal area are more likely to develop pre-diabetic condition known as hyperinsulinemia. And studies have shown that insulin receptors can promote the growth of breast cancer cells,” said Holly R. Harris from Brigham and Women’s Hospital and Harvard Medical School in Boston,Friday (12/17/2010).
Many previous studies that show that belly fat causes more health problems than fat on other parts of the body, among other triggers high cholesterol, high insulin and high blood pressure which increases the risk of getting diabetes, heart disease, stroke and dementia (senile).
Recent research also revealed that pre-menopausal women who have excess fat in the abdomen distended stomach alias will face a higher risk for breast cancer, particularly estrogen receptor (ER)-negative.
Breast cancer estrogen receptor (ER)-negative means that the cancer does not have receptors for the hormone estrogen in women, so that the hormone does not stimulate the cancer to grow.
In this latest study, Harris and his colleagues focused on data from over 116,000 women who have been enrolled in the Nurses Health Study II since 1989, including waist and hip circumference records.
Previously, the research team showed that body fat composition (as indicated by body mass index or BMI) has a complex relationship with cancer risk.
For example, a higher BMI had previously been associated with increased risk for breast cancer in post-menopausal, but not pre-menopausal breast cancer, as shown in the current research.
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